Torsades de Pointes during Treatment of Tachycardia-Induced Cardiomyopathy

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[Torsades de pointes during methadone treatment].

Methadone is a synthetic opioid that has been used successfully to treat heroin addiction and chronic pain. It is usually well tolerated and has few side effects. Recently, an association with torsade de pointes has been reported. We present 4 cases of torsade de pointes during methadone treatment.

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Torsades de Pointes During Methadone Treatment

Four patients (3 men, 1 woman) with no known history of heart disease were seen in the emergency room for syncopal episodes (Table). All were under longterm methadone therapy, although only 1 was receiving >200 mg/day. Three of these patients were infected with human immunodeficiency virus (HIV), but only 1 was on antiretroviral therapy. The electrocardiographic recordings and monitoring showed...

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Sepsis-Induced Takotsubo Cardiomyopathy Leading to Torsades de Pointes

Background. Takotsubo cardiomyopathy (TCM) is sudden and reversible myocardial dysfunction often attributable to physical or emotional triggers. Case Report. We describe a 51-year-old man presented to emergency department with sepsis from urinary tract infection (UTI). He was placed on cefepime for UTI and non-ST-elevation myocardial infarction protocol given elevated troponins with chest pain....

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Methadone-induced Torsades de pointes.

Torsades de pointes is a polymorphic ventricular tachycardia that can quickly evolve into ventricular fibrillation and sudden death. This arrhythmia often occurs secondary to medication- induced cardiac repolarization dysfunction with resultant prolonged QTc interval on ECG. Numerous medications can predispose patients to this deadly tachycardia. We report a case of methadone-induced Torsades d...

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Torsades de pointes induced by antibiotics.

BACKGROUND Several frequently used antibiotics are associated with an arrhythmia called "torsades de pointes" (TdP). This potentially fatal arrhythmia is considered unpredictable. METHODS In order to investigate the prevalence of risk factors for TdP prior to initiation of antibiotic therapy, we conducted a literature search for all published reports on TdP induced by antibiotics and we asked...

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ژورنال

عنوان ژورنال: Korean Journal of Critical Care Medicine

سال: 2014

ISSN: 1229-4802,2234-3261

DOI: 10.4266/kjccm.2014.29.1.19